数据库名称：ADNI
数据库简述：Alzheimer Disease Neuroimaging Initiative
所属国家/地区：United States
数据库主要信息：Alzheimer Disease Neuroimaging Initiative (ADNI) aim to gain new biological insights in the disease etiology. We report here an untargeted lipidomics of serum specimens of 806 subjects within the ADNI1 cohort (188 AD, 392 mild cognitive impairment and 226 cognitively normal subjects) along with 83 quality control samples. Lipids were detected and measured using an ultra-high-performance liquid chromatography quadruple/time-of-flight mass spectrometry (UHPLC-QTOF MS) instrument operated in both negative and positive electrospray ionization modes. The dataset includes a total 513 unique lipid species out of which 341 are known lipids. For over 95% of the detected lipids, a relative standard deviation of better than 20% was achieved in the quality control samples, indicating high technical reproducibility. Association modeling of this dataset and available clinical, metabolomics and drug-use data will provide novel insights into the AD etiology
建立年份：2018
联系信息：Contact information
University/Institution:
Duke University
Address:
Department of Psychiatry and Behavioral Sciences; Department of Medicine and the Duke Institute for Brain Sciences, Duke University, Durham, NC, 27708 USA
City:
Province/State:
Country/Region:
United States
Contact name (PI/Team):
Rima Kaddurah-Daouk
Contact email (PI/Helpdesk):
kaddu001@mc.duke.edu
