数据库名称:Brain Catalog
数据库简述:a One-Stop Shop for Brain-related Traits
所属国家/地区:China
数据库主要信息:Brain Catalog is a comprehensive resource for genetic landscape of brain disorders and related phenotypes. Currently, Brain Catalog includes the following components: 1. Variant annotation by three software VEP, snpEff and ANNOVAR. 2. Gene-based and gene set analysis by MAGMA. 3. Heritability, heritability enrichment and heritability correlation analysis by two software LDSC and LDAK. 4. Enrichment analysis of associated-trait loci in regulatory and functional annotations by GARFIELD and S-LDSC. 5. Finemapping analysis by four fine-mapping methods ABF, FINEMAP, SuSiE and PolyFun + SuSiE. 6. Gene-based TWAS association by three software S-PrediXcan, UTMOST and JTI. 7. Causal inference and colocalization between six kinds of molecule-QTLs and brain traits, and also the causal effect of exposure traits on outcome traits.
建立年份:2022
联系信息:Contact information
University/Institution:
Beijing Institute of Genomics, Chinese Academy of Sciences
Address:
No.1 Beichen West Road, Chaoyang District, Beijing
City:
Beijing
Province/State:
Beijing
Country/Region:
China
Contact name (PI/Team):
Peilin Jia
Contact email (PI/Helpdesk):
pjia@big.ac.cn