数据库名称：Cancer-mbQTL
数据库简述：Pan-Cancer Analysis of Microbiome Quantitative Trait Loci
所属国家/地区：China
数据库主要信息：This study systematically identified 38,660 mbQTLs across cancers, ranging 50 in endometrial carcinoma to 3,133 in thyroid carcinoma. Furthermore, a strong enrichment of mbQTLs was observed among transcription factor binding sites and chromatin regulatory elements, such as H3K27ac. Notably, mbQTLs were significantly enriched in cancer genome-wide association studies (GWAS) loci and explained an average of 2% for cancer heritability, indicating that mbQTLs could provide additional insights into cancer etiology. Correspondingly, 24,443 mbQTLs overlapping with GWAS linkage disequilibrium regions were identified. Survival analyses identified 318 mbQTLs associated with patient overall survival.
建立年份：2022
联系信息：Contact information
University/Institution:
Wuhan University
Address:
Department of Epidemiology and Biostatistics, School of Public Health, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
City:
Province/State:
Country/Region:
China
Contact name (PI/Team):
Jianbo Tian
Contact email (PI/Helpdesk):
tianjb@whu.edu.cn
