数据库名称：CenhANCER
数据库简述：Cancer Enhancer Database
所属国家/地区：China
数据库主要信息：Here, we developed CenhANCER, a comprehensive cancer enhancer database, based on H3K27ac ChIP-Seq datasets of 805 primary cancer tissues and 671 cancer cell lines across 49 cancer types. In total, we identified 29,815,953 typical enhancers and 516,447 super enhancers (SE) for the primary tissues, and 27,213,455 typical enhancers, 461,964 super enhancers for the cell lines. To strengthen the regulatory roles of the super-enhancers, we further integrated expression quantitative trait locus (eQTLs) , and risk SNPs into CenhANCER. We also identified transcription factors, whose binding sites were enriched for enhancers in each sample, which are potential therapeutic targets.
建立年份：2021
联系信息：Contact information
University/Institution:
Huazhong University of Science and Technology
Address:
Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, 97 Buxin Road, Shenzhen 518000, China.
City:
Province/State:
Country/Region:
China
Contact name (PI/Team):
ShanShan Cheng
Contact email (PI/Helpdesk):
sscheng@hustedu.cn
