数据库名称：Chromosome 22
数据库简述：
所属国家/地区：United States
数据库主要信息：A DNA microarray representing nearly all of the unique sequences of human Chromosome 22 was constructed and used to measure global-transcriptional activity in placental poly(A)(+) RNA. We found that many of the known, related and predicted genes are expressed. More importantly, our study reveals twice as many transcribed bases as have been reported previously. Many of the newly discovered expressed fragments were verified by RNA blot analysis and a novel technique called differential hybridization mapping (DHM). Interestingly, a significant fraction of these novel fragments are expressed antisense to previously annotated introns. The coding potential of these novel expressed regions is supported by their sequence conservation in the mouse genome. This study has greatly increased our understanding of the biological information encoded on a human chromosome.
建立年份：2003
联系信息：Contact information
University/Institution:
Yale University
Address:
City:
Province/State:
Country/Region:
United States
Contact name (PI/Team):
Michael Snyder
Contact email (PI/Helpdesk):
michael.snyder@yale.edu
