数据库名称:CjPCA
数据库简述:Callithrix jacchus Primate Cell Atlas
所属国家/地区:United States
数据库主要信息:To understand the cellular composition and region-specific specialization of white matter – a disease-relevant, glia-rich tissue highly expanded in primates relative to rodents – we profiled transcriptomes of ~500,000 nuclei from 19 tissue types of the central nervous system of healthy common marmoset and mapped 87 subclusters spatially onto a 3D MRI atlas. We performed cross-species comparison, explored regulatory pathways, modeled regional intercellular communication, and surveyed cellular determinants of neurological disorders. Here, we analyze this resource and find strong spatial segregation of microglia, oligodendrocyte progenitor cells, and astrocytes.
建立年份:2022
联系信息:Contact information
University/Institution:
National Institutes of Health
Address:
Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD USA
City:
Province/State:
Country/Region:
United States
Contact name (PI/Team):
Daniel S. Reich
Contact email (PI/Helpdesk):
daniel.reich@nih.gov