CPAD数据库介绍

数据库名称:CPAD

数据库简述:Curated Protein Aggregation Database

所属国家/地区:India

数据库主要信息:Curated Protein Aggregation Database (CPAD), has collected results from experimental studies performed by scientific community aimed at understanding protein/peptide aggregation. CPAD contains more than 2300 experimentally observed aggregation rates upon mutations in known amyloidogenic proteins. Each entry includes numerical values for the following parameters: change in rate of aggregation as measured by fluorescence intensity or turbidity, name and source of the protein, Uniprot and Protein Data Bank codes, single point as well as multiple mutations, and literature citation. The data in CPAD has been supplemented with five different types of additional information: (i) Amyloid fibril forming hexa-peptides, (ii) Amorphous β-aggregating hexa-peptides, (iii) Amyloid fibril forming peptides of different lengths, (iv) Amyloid fibril forming hexa-peptides whose crystal structures are available in the Protein Data Bank (PDB) and (v) Experimentally validated aggregation prone regions found in amyloidogenic proteins

建立年份:2016

联系信息:Contact information

University/Institution:
Indian Institute of Technology Madras

Address:
Department of Biotechnology, Bhupat and Jyoti Metha School of Biosciences, Indian Institute of Technology Madras, Chennai, 600036, India

City:
Chennai

Province/State:

Country/Region:
India

Contact name (PI/Team):
M. Michael Gromiha

Contact email (PI/Helpdesk):
gromiha@iitm.ac.in

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