数据库名称：E3 Ligases
数据库简述：Database of human E3 ubiquitin ligases
所属国家/地区：United States
数据库主要信息：A comprehensive curated set of E3 ubiquitin ligases expressed in the human genome, is freely accessible as an online webpage, which provides a resource that can be used by other investigators. Second, it reports a ranking of E3 ligases with regard to the probability that they ubiquitinate AQP2 in the mammalian collecting duct. A Bayesian approach was used to probabilistically rank the ubiquitin ligases based on six independent, large-scale, systems-level datasets and data integration approach led to the identification of Nedd4 and Nedd4l as the highest ranked candidate ligases.
建立年份：2016
联系信息：Contact information
University/Institution:
National Heart, Lung, and Blood Institute
Address:
Epithelial Systems Biology Laboratory, Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland
City:
Province/State:
Maryland
Country/Region:
United States
Contact name (PI/Team):
Mark A. Knepper
Contact email (PI/Helpdesk):
knepperm@nhlbi.nih.gov
