数据库名称：eccDNA Atlas
数据库简述：data portal of eccDNAs/ecDNAs across multiple species
所属国家/地区：China
数据库主要信息：Extrachromosomal circular DNAs (eccDNAs) represent a large category of nonmitochondrial and nonplasmid circular extrachromosomal DNA, and eccDNAs play an indispensable role involved in various aspects such as tumorigenesis, immune responses and biomarker, etc. Here, we developed eccDNA Atlas, a user-friendly database of eccDNAs that aims to provide a high-quality and integrated resource for browsing, searching and analyzing eccDNAs such as sequence, function/characteristic, validation strategies, etc. from multiple species. eccDNA Atlas currently containing 629,987 eccDNAs and 8,221 ecDNAs manually curated from literatures and 1,105 ecDNAs predicted by AmpliconArchitect based on WGS data involved in 66 diseases, 57 tissues and 319 cell lines. Furthermore, abundant annotations and analyzing utilities were provided to explore eccDNA Atlas eccDNAs or user-defined eccDNAs such as oncogenes, typical enhancers, super enhancers, gene expression, survival, genome visualization, etc.
建立年份：2022
联系信息：Contact information
University/Institution:
Southwest Jiaotong University
Address:
School of Life Sciences and Engineering,Southwest Jiaotong University, Chengdu 610000, China
City:
Chengdu
Province/State:
Sichuan
Country/Region:
China
Contact name (PI/Team):
Zhiyun Guo
Contact email (PI/Helpdesk):
zhiyunguo@swjtu.edu.cn
