数据库名称:FstSNP-HapMap3
数据库简述:
所属国家/地区:United States
数据库主要信息:The International HapMap Project has recently made available genotypes and frequency data for phase 3 (NCBI build 36, dbSNP b129) of the HapMap providing an enriched genotype dataset for approximately 1.6 million single nucleotide polymorphisms (SNPs) from 1,115 individuals with ancestry from parts of Africa, Asia, Europe, North America and Mexico. In the present study, we aim to facilitate pharmacogenetics studies by providing a database of SNPs with high population differentiation through a genomewide test on allele frequency variation among 11 HapMap3 samples. Common SNPs with minor allele frequency greater than 5% from each of 11 HapMap3 samples were included in the present analysis. The population differentiation is measured in terms of fixation index (Fst), and the SNPs with Fst values over 0.5 were defined as highly differentiated SNPs.
建立年份:2008
联系信息:Contact information
University/Institution:
University of Chicago
Address:
City:
Province/State:
Country/Region:
United States
Contact name (PI/Team):
Mary Eileen Dolan
Contact email (PI/Helpdesk):
edolan@medicine.bsd.uchicago.edu