数据库名称:FusionCancer
数据库简述:
所属国家/地区:China
数据库主要信息:Fusion gene is a chimera product due to the consolidation of two separate genes, which can occur as a consequence of chromosomal structural changes, such as inversion, deletion, amplification or inter-chromosomal/intra-chromosomal translocation [1]. Gene fusion can bring dramatic expression changes compared to previous separate genes because of the regulatory domain displacement, and the resulting chimeric protein-coding transcript will either lose its original function or work into a scabbed protein with functions descended from both its ancestors.
建立年份:2015
联系信息:Contact information
University/Institution:
East China Normal University
Address:
Institute of Molecular Ecology and Evolution, SKLEC & IECR, East China Normal University, Shanghai, China
City:
Shanghai
Province/State:
Shanghai
Country/Region:
China
Contact name (PI/Team):
Yunjin Wang
Contact email (PI/Helpdesk):
yunjinwang1222@gmail.com