数据库名称:hu.MAP
数据库简述:Human Protein Complex Map
所属国家/地区:United States
数据库主要信息:Proteins interact with each other and organize themselves into macromolecular machines (ie. complexes) to carry out essential functions of the cell. We have a good understanding of a few complexes such as the proteasome and the ribosome but currently we have an incomplete view of all protein complexes as well as their functions. The hu.MAP attempts to address this lack of understanding by integrating several large scale protein interaction datasets to obtain the most comprehensive view of protein complexes. Specifically, we integrated two large scale affinity purification mass spectrometry (AP/MS) datasets from Bioplex and Hein et al. with our dataset of large scale biochemical fractionations (Wan et al) and produced a complex map with over 4k complexes.
建立年份:2017
联系信息:Contact information
University/Institution:
University of Texas at Austin
Address:
Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX
City:
Province/State:
Country/Region:
United States
Contact name (PI/Team):
Edward M Marcotte
Contact email (PI/Helpdesk):
marcotte@icmb.utexas.edu