数据库名称：IEAtlas
数据库简述：atlas of HLA-presented immunogenic epitopes derived from non-coding regions
所属国家/地区：China
数据库主要信息：IEAtlas reanalyzed publicly available mass spectrometry-based HLA immunopeptidome datasets against our integrated benchmarked non-canonical open reading frame information. The current IEAtlas identified 245 870 non-canonical epitopes binding to HLA-I/II allotypes across 15 cancer types and 30 non-cancerous tissues, greatly expanding the cancer immunopeptidome. IEAtlas further evaluates the immunogenicity via several commonly used immunogenic features, including HLA binding affinity, stability and T-cell receptor recognition. In addition, IEAtlas provides the biochemical properties of epitopes as well as the clinical relevance of corresponding genes across major cancer types and normal tissues.
建立年份：2023
联系信息：Contact information
University/Institution:
Harbin Medical University
Address:
194 Xuefu Road, Harbin 150081
City:
Province/State:
Country/Region:
China
Contact name (PI/Team):
Juan Xu
Contact email (PI/Helpdesk):
xujuanbiocc@ems.hrbmu.edu.cn
