数据库名称：iSyTE
数据库简述：integrated Systems Tool for Eye gene discovery
所属国家/地区：United States
数据库主要信息：To expedite gene discovery in eye development and its associated defects, we previously developed a bioinformatics resource-tool iSyTE (integrated Systems Tool for Eye gene discovery). However, iSyTE is presently limited to lens tissue and is predominantly based on transcriptomics datasets. Therefore, to extend iSyTE to other eye tissues on the proteome level, we performed high-throughput tandem mass spectrometry (MS/MS) on mouse embryonic day (E)14.5 retina and retinal pigment epithelium combined tissue and identified an average of 3300 proteins per sample (n = 5). High-throughput expression profiling-based gene discovery approaches-involving either transcriptomics or proteomics-pose a key challenge of prioritizing candidates from thousands of RNA/proteins expressed.
建立年份：2023
联系信息：Contact information
University/Institution:
University of Delaware
Address:
Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE, 19713, USA.
City:
Province/State:
Country/Region:
United States
Contact name (PI/Team):
Salil A Lachke
Contact email (PI/Helpdesk):
salil@udel.edu
