数据库名称：ITxF
数据库简述：
所属国家/地区：Germany
数据库主要信息：Repetitive nucleic acid sequences are often prone to form secondary structures distinct from B-DNA. Prominent examples of such structures are DNA triplexes. We observed that certain intrastrand triplex motifs are highly conserved and abundant in prokaryotic genomes. A systematic search of 5246 different prokaryotic plasmids and genomes for intrastrand triplex motifs was conducted and the results summarized in the ITxF database available online at http://bioinformatics.uni-konstanz.de/utils/ITxF/. Next we investigated biophysical and biochemical properties of a particular G/C-rich triplex motif (TM) that occurs in many copies in more than 260 bacterial genomes by CD and nuclear magnetic resonance spectroscopy as well as in vivo footprinting techniques
建立年份：2015
联系信息：Contact information
University/Institution:
University of Konstanz
Address:
Department of Chemistry and Konstanz Research School Chemical Biology (KoRS-CB), University of Konstanz, Universitätsstrasse 10, 78457 Konstanz, Germany
City:
Province/State:
Country/Region:
Germany
Contact name (PI/Team):
Hartig JS
Contact email (PI/Helpdesk):
joerg.hartig@uni-konstanz.de
