数据库名称：MeDBA
数据库简述：Metalloenzyme Data Bank and Analysis Platform
所属国家/地区：China
数据库主要信息：The Metalloenzyme Data Bank and Analysis (MeDBA) is an integrated, distinctive, practicable, user-friendly platform and provides metalloenzyme-focused data bank and analysis tools, which will help understand and investigate metalloenzyme-involved contents, and will promote and bridge metalloenzyme-related areas (e.g., biological chemistry, structural and chemical biology, synthetic biology, bioinorganic chemistry, medicinal chemistry, computational chemistry and drug discovery). The current version of MeDBA contains 82,540 metalloenzymes, 440,631 ligands (431,014 bioactive molecules, 2,243 substrates/products, 566 drugs, 6,942 drug candidates, and 1,415 PROTACs), 10,613 metalloenzyme-ligand complexes, 21,616 metal sites, and 844 MBPs. – Data bank. To shed light on metalloenzyme-centric knowledges, MeDBA integrates comprehensive information of metalloenzymes (e.g., related diseases, structures, metal sites), ligands (e.g., bioactive molecules, substrates/products, drugs and drug candidates) and metalloenzyme-ligand associations (e.g., MBP, metalloenzyme-ligand complexes), which are provided for users to freely search, browse, download and analyze. Notably, the elaborately excavated MBPs are available to link different metalloenzymes and help establish new metalloenzyme-ligand associations. – Analysis servers. To conveniently use the metalloenzyme data bank, metalloenzyme-specific analysis servers are provided, including 3D visualization of metalloenzyme structures, structure/metal active site comparison, substructure search for ligands and MBPs, and metalloenzyme profiling. MeDBA is available at https://medba.ddtmlab.org/.
建立年份：2022
联系信息：Contact information
University/Institution:
Sichuan University
Address:
No.24 South Section 1, Yihuan Road
City:
Chengdu
Province/State:
SiChuan
Country/Region:
China
Contact name (PI/Team):
Yu JunLin
Contact email (PI/Helpdesk):
vicfisher6072@163.com
