数据库名称:MENDA
数据库简述:metabolite network of depression database
所属国家/地区:China
数据库主要信息:MENDA provide a panoramic and systematic view of metabolic characterization in the context of depression by developing a knowledge base of metabolic characterization in depression. To this end, we manually integrated available knowledge for depressed patients and animal models, as well as metabolic changes resulting from treatments, in a new metabolite-disease association database called the metabolite network of depression database (MENDA; http://menda.cqmu.edu.cn:8080/index.php). The standardized data extraction process was used for data collection, a multi-faceted annotation scheme was developed and a user-friendly search engine and web interface were integrated for database access. To facilitate data analysis and interpretation based on MENDA, we also proposed a systematic analytical framework. Case studies were provided that identified the consistently altered metabolites using the vote-counting method, and which captured the underlying molecular mechanism using pathway and network analyses
建立年份:2019
联系信息:Contact information
University/Institution:
The First Affiliated Hospital of Chongqing Medical University
Address:
Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
City:
Chongqing
Province/State:
Chongqing
Country/Region:
China
Contact name (PI/Team):
Peng Xie
Contact email (PI/Helpdesk):
xiepeng@cqmu.edu.cn