数据库名称:OAF
数据库简述:
所属国家/地区:Ireland
数据库主要信息:We have developed a computer tool, OAF (ODC antizyme finder) for identifying antizyme encoding sequences in spliced or intronless nucleic acid sequenes. OAF utilizes a combination of profile hidden Markov models (HMM) built separately for the products of each open reading frame constituting the entire antizyme coding sequence. Profile HMMs are based on a set of 218 manually assembled antizyme sequences. To distinguish between antizyme paralogs and orthologs from major phyla, antizyme sequences were clustered into twelve groups and specific combinations of profile HMMs were designed for each group. OAF has been tested on the current version of dbEST, where it identified over six thousand Expressed Sequence Tags (EST) sequences encoding antizyme proteins (over two thousand antizyme CDS in these ESTs are non redundant).
建立年份:2008
联系信息:Contact information
University/Institution:
University College Dublin
Address:
City:
Province/State:
Country/Region:
Ireland
Contact name (PI/Team):
Bekaert M
Contact email (PI/Helpdesk):
mbekaert@gmail.com