PharMeBINet数据库介绍

数据库名称:PharMeBINet

数据库简述:PharMeBINet: The heterogeneous pharmacological medicalbiochemical network

所属国家/地区:Germany

数据库主要信息:Heterogeneous biomedical pharmacological databases are important for multiple fields in bioinformatics. Hetionet is a freely available database combining diverse entities and relationships from 29 public resources. Therefore, it is used as the basis for this project. 19 additional pharmacological medical and biological databases such as CTD, DrugBank, and ClinVar are parsed and integrated into Neo4j. Afterwards, the information is merged into the Hetionet structure. Different mapping methods are used such as external identification systems or name mapping. The resulting open-source Neo4j database PharMeBINet has 2,869,407 different nodes with 66 labels and 15,883,653 relationships with 208 edge types. It is a heterogeneous database containing interconnected information on ADRs, diseases, drugs, genes, gene variations, proteins, and more. Relationships between these entities represent drug-drug interactions or drug-causes-ADR relations, to name a few. It has much potential for developing further data analyses including machine learning applications.

建立年份:2022

联系信息:Contact information

University/Institution:
Bielefeld University

Address:
Bielefeld University, Bioinformatics/Medical Informatics Department, Bielefeld, 33615, Germany

City:

Province/State:

Country/Region:
Germany

Contact name (PI/Team):
Cassandra Königs

Contact email (PI/Helpdesk):
c.koenigs@uni-bielefeld.de

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