数据库名称:TIGER
数据库简述:A Web Portal of Tumor Immunotherapy Gene Expression Resource
所属国家/地区:China
数据库主要信息:Here, we present TIGER, a tumor immunotherapy gene expression resource, which contains bulk transcriptome data of 1508 tumor samples with clinical immunotherapy outcomes and 11,057 tumor/normal samples without clinical immunotherapy outcomes, as well as single-cell transcriptome data of 2,116,945 immune cells from 655 samples. TIGER provides many useful modules for analyzing collected and user-provided data. Using the resource in TIGER, we identified a tumor-enriched subset of CD4+ T cells. Patients with melanoma with a higher signature score of this subset have a significantly better response and survival under immunotherapy.
建立年份:2022
联系信息:Contact information
University/Institution:
Sun Yat-sen University
Address:
State Key Laboratory of Oncology in South China, Cancer Center, Collaborative Innovation Center for Cancer Medicine, School of Life Sciences, Sun Yat-sen University, Guangzhou 510060, China.
City:
Province/State:
Country/Region:
China
Contact name (PI/Team):
Zhixiang Zuo
Contact email (PI/Helpdesk):
zuozhx@sysucc.org.cn