基因名称：ABCC10 （ATP binding cassette subfamily C member 10）
别名： EST182763,MRP7,SIMRP7
基因ID：89845
Chromosome(GRCh37) ：6 Start: 43395104 End: 43418168 Strand: 1
信号通路：
靶向药：
化疗药：紫杉醇
简介：该基因编码的蛋白是ATP结合盒（ABC）转运蛋白的超家族成员。ABC蛋白通过细胞外膜和细胞内膜转运各种分子。ABC基因被分为7个不同的亚家族（abc1、mdr/tap、mrp、ald、oabp、gcn20和white）。这种ABC全转运体是MRP亚家族的一员，涉及多药耐药。已发现编码该基因不同亚型的多种转录变体。The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.
ABCC10突变与药物：
EXPRESSION
药物：
紫杉醇 疾病：
非小细胞肺癌
