基因名称:ACOT13 (acyl-CoA thioesterase 13)
别名: HT012,THEM2,PNAS-27
基因ID:55856
Chromosome(GRCh37) :6 Start: 24667263 End: 24705297 Strand:
信号通路:
靶向药:
化疗药:
简介:这个基因编码硫酯酶超家族的一个成员在人类中,这种蛋白质与微管共同定位,是维持细胞增殖所必需的同源小鼠蛋白形成同四聚体,与线粒体有关。小鼠蛋白具有中、长链酰基辅酶A硫酯酶的功能。已发现该基因编码不同亚型的多个转录变体。[由RefSeq提供,2009年5月]This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2009]
ACOT13突变与药物: