基因名称：ADRB1 （adrenoceptor beta 1）
别名： RHR,B1AR,FNSS2,ADRB1R,BETA1AR
基因ID：153
Chromosome(GRCh37) ：10 Start: 115803806 End: 115806667 Strand:
信号通路：
靶向药：
化疗药：
简介：肾上腺素能受体（α1、α2、β1和β2亚型）是鸟嘌呤核苷酸结合调节蛋白偶联受体的一个原型家族，介导肾上腺素和神经递质去甲肾上腺素的生理效应。β1肾上腺素受体主要位于心脏。该基因的特异性多态性已被证明影响静息心率，并可能与心力衰竭有关。[由RefSeq提供，2019年9月]The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Sep 2019]
ADRB1突变与药物：
