基因名称:ARFRP1 (ADP ribosylation factor related protein 1)
别名: ARP,Arp1,ARL18
基因ID:10139
Chromosome(GRCh37) :20 Start: 62329995 End: 62339365 Strand:
信号通路: 细胞增殖
靶向药:
化疗药:
简介:该基因编码的蛋白是一种膜相关gtp酶,定位于质膜,与adp核糖基化因子(arf)和arf样蛋白(arl)有关。这个基因在跨高尔基体网络和内切体之间的膜运输中起作用。另外,还发现了编码不同亚型的剪接转录变体。[由RefSeq提供,2012年5月]The protein encoded by this gene is a membrane-associated GTP-ase which localizes to the plasma membrane and is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) proteins. This gene plays a role in membrane trafficking between the trans-Golgi network and endosomes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2012]
ARFRP1突变与药物: