基因名称:ASB18 (ankyrin repeat and SOCS box containing 18)
别名: ASB-18
基因ID:401036
Chromosome(GRCh37) :2 Start: 237103515 End: 237172988 Strand:
信号通路:
靶向药:
化疗药:
简介:由该基因编码的蛋白质是一个含有ankyrin重复序列和SOCS盒(ASB)的蛋白质家族的成员它们包含锚定蛋白重复序列和SOCS盒结构域socs盒用于将细胞因子信号(socs)蛋白的抑制因子及其结合伙伴与elongin b和c复合物结合,可能将其作为降解的靶点。[由RefSeq提供,2017年2月]The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. [provided by RefSeq, Feb 2017]
ASB18突变与药物: