基因名称:ASH1L (ASH1 like histone lysine methyltransferase)
别名: ASH1,KMT2H,MRD52,ASH1L1
基因ID:55870
Chromosome(GRCh37) :1 Start: 155305052 End: 155532324 Strand:
信号通路:
靶向药:
化疗药:
简介:该基因编码转录激活因子trithorax组的一个成员该蛋白包含四个AT-hooks、一个集合结构域、一个PHD-finger基序和一个bromodomain它局限于细胞核中的许多小斑点,也局限于细胞-细胞紧密连接处[由RefSeq提供,2008年7月]This gene encodes a member of the trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions. [provided by RefSeq, Jul 2008]
ASH1L突变与药物: