基因名称：ATP12A （ATPase H+/K+ transporting non-gastric alpha2 subunit）
别名： HK,ATP1AL1,H-K-ATPase
基因ID：479
Chromosome(GRCh37) ：13 Start: 25254549 End: 25285923 Strand:
信号通路：
靶向药：
化疗药：
简介：该基因编码的蛋白属于P型阳离子转运atp酶家族该基因编码哇巴因敏感的h~+k~+atp酶的一个催化亚基，该亚基催化atp水解，并与h~+k~+k~+h~+k~+h~+k~+h~+k~+h~+k~+k~+h~+k~+h~+k~+h~+k~+atp酶交换。它还负责钾在各种组织中的吸收。已经发现了两个编码不同亚型的转录变体。[由RefSeq提供，2010年6月]The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This gene encodes a catalytic subunit of the ouabain-sensitive H+/K+ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for potassium absorption in various tissues. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
ATP12A突变与药物：
