基因名称:BCORL1 (BCL6 corepressor like 1)
别名: SHUVER,BCoR-L1,CXorf10
基因ID:63035
Chromosome(GRCh37) :X Start: 129114277 End: 129192058 Strand:
信号通路: 肿瘤干细胞
靶向药:
化疗药:
简介:这个基因编码的蛋白质是一种转录共加压因子,通过DNA结合蛋白与启动子区相连。编码的蛋白质可以与几种不同的II类组蛋白脱乙酰酶相互作用来抑制转录。已经发现了两个编码不同亚型的转录变体。[由RefSeq提供,2010年5月]The protein encoded by this gene is a transcriptional corepressor that is found tethered to promoter regions by DNA-binding proteins. The encoded protein can interact with several different class II histone deacetylases to repress transcription. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
BCORL1突变与药物: