基因名称:CBR3 (carbonyl reductase 3)
别名: hCBR3,SDR21C2,HEL-S-25
基因ID:874
Chromosome(GRCh37) :21 Start: 37506614 End: 37518860 Strand:
信号通路:
靶向药:
化疗药:
简介:羰基还原酶3催化大量生物和药理活性羰基化合物还原为相应的醇。酶被分类为单体NADPH依赖的氧化还原酶。CBR3包含三个外显子,跨越11.2千碱基,与另一个羰基还原酶基因CBR1紧密相连。[由RefSeq提供,2008年7月]Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene – CBR1. [provided by RefSeq, Jul 2008]
CBR3突变与药物: