基因名称：CDX2 （caudal type homeobox 2）
别名： CDX-3,CDX2/AS,CDX3
基因ID：1045
Chromosome(GRCh37) ：13 Start: 28536274 End: 28545276 Strand: -1
信号通路：
靶向药：
化疗药：
简介：该基因是尾相关同源盒转录因子基因家族的成员。编码蛋白是参与细胞生长和分化的肠道特异性基因的主要调节因子。这种蛋白也在肠道的早期胚胎发育中起作用。这种基因的异常表达与肠道炎症和肿瘤发生有关。This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.
CDX2突变与药物：
EXPRESSION
药物：
Ziv-阿柏西普
疾病：
“结直肠癌”
