基因名称：CFLAR （CASP8 and FADD like apoptosis regulator）
别名： CASH,CASP8AP1,CLARP,Casper,FLAME,FLAME-1,FLAME1,FLIP,I-FLICE,MRIT,c-FLIP,c-FLIPL,c-FLIPR,c-FLIPS
基因ID：8837
Chromosome(GRCh37) ：2 Start: 201980827 End: 202041410 Strand: 1
信号通路：
靶向药：
化疗药：比卡鲁胺
简介：该基因编码的蛋白是一种细胞凋亡调节因子，其结构与caspase-8相似。然而，编码蛋白缺乏半胱天冬酶活性，似乎自己被半胱天冬酶8分裂成两个肽。该基因有几种编码不同亚型的转录变体，并且存在更多变体的部分证据。The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.
CFLAR突变与药物：
EXPRESSION
药物：
比卡鲁胺 疾病：
前列腺癌
