基因名称:CHD1 (chromodomain helicase DNA binding protein 1)
别名: CHD-1,PILBOS
基因ID:1105
Chromosome(GRCh37) :5 Start: 98189689 End: 98264522 Strand:
信号通路:
靶向药:
化疗药:
简介:CHD蛋白家族的特征是存在染色质组织修饰域和SNF2相关的螺旋酶/ATPase结构域chd基因可能通过改变染色质结构来改变基因表达,从而改变转录设备对其染色体dna模板的访问。[由RefSeq提供,2008年7月]The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. [provided by RefSeq, Jul 2008]
CHD1突变与药物: