CKS1B靶向药基因

基因名称:CKS1B  (CDC28 protein kinase regulatory subunit 1B)

别名: CKS1,ckshs1,PNAS-16,PNAS-18
基因ID:1163
Chromosome(GRCh37) :1 Start: 154947118 End: 154951725 Strand:
信号通路:
靶向药:
化疗药:

简介:cks1b蛋白与细胞周期蛋白依赖性激酶的催化亚单位结合,对其生物学功能至关重要。cks1b mrna在hela细胞周期中以不同的方式表达,反映了编码蛋白的特殊作用。该基因至少有两个转录变体被鉴定出来,而且似乎只有其中一个编码蛋白质[由RefSeq提供,2008年9月]CKS1B protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein. [provided by RefSeq, Sep 2008]
CKS1B突变与药物:

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