基因名称:CREB3L2 (cAMP responsive element binding protein 3 like 2)
别名: BBF2H7
基因ID:64764
Chromosome(GRCh37) :7 Start: 137559725 End: 137686847 Strand:
信号通路:
靶向药:
化疗药:
简介:这个基因编码绿洲bzip转录因子家族的一个成员。这个家族的成员可以二聚体,但只能形成同二聚体。编码的蛋白质是一种转录激活物。在一些肿瘤中,7号染色体上的这个基因和16号染色体上的肉瘤融合基因之间存在易位。已发现该基因编码不同亚型的多个转录变体。[由RefSeq提供,2011年12月]This gene encodes a member of the oasis bZIP transcription factor family. Members of this family can dimerize but form homodimers only. The encoded protein is a transcriptional activator. Translocations between this gene on chromosome 7 and the gene fused in sarcoma on chromosome 16 can be found in some tumors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
CREB3L2突变与药物: