基因名称:CRNKL1 (crooked neck pre-mRNA splicing factor 1)
别名: CLF,CRN,Clf1,HCRN,SYF3,MSTP021
基因ID:51340
Chromosome(GRCh37) :20 Start: 20015005 End: 20036690 Strand:
信号通路:
靶向药:
化疗药:
简介:果蝇曲颈基因(crn)是胚胎发生的关键基因,被认为参与细胞周期的进程和mrna前剪接。由这个人类基因座编码的蛋白质被发现定位于细胞核中的前mrna剪接复合物,是前mrna剪接所必需的。另外,已经描述了剪接转录变体。[由RefSeq提供,2013年7月]The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. A protein encoded by this human locus has been found to localize to pre-mRNA splicing complexes in the nucleus and is necessary for pre-mRNA splicing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2013]
CRNKL1突变与药物: