基因名称:CYSLTR2 (cysteinyl leukotriene receptor 2)
别名: HG57,CYSLT2,GPCR21,HPN321,CYSLT2R,KPG_011,hGPCR21,PSEC0146
基因ID:57105
Chromosome(GRCh37) :13 Start: 49227847 End: 49283498 Strand:
信号通路:
靶向药:
化疗药:
简介:半胱氨酸白三烯ltc4、ltd4和lte4是人类支气管哮喘的重要介质。药理学研究已经确定,胱氨酰白三烯至少激活2个受体,由该基因和cysltr1编码的蛋白质。该编码受体是g蛋白偶联受体超家族的成员。它似乎在内分泌和心血管系统中起主要作用。[由RefSeq提供,2008年7月]The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems. [provided by RefSeq, Jul 2008]
CYSLTR2突变与药物: