DHX35靶向药基因

基因名称:DHX35  (DEAH-box helicase 35)

别名: DDX35,C20orf15,KAIA0875
基因ID:60625
Chromosome(GRCh37) :20 Start: 37590981 End: 37668366 Strand:
信号通路:
靶向药:
化疗药:

简介:以保守基序Asp-Glu-Ala-Asp(DEAD)为特征的死盒蛋白是假定的RNA解旋酶它们参与了一些涉及rna二级结构改变的细胞过程,如翻译起始、核和线粒体剪接、核糖体和剪接体组装。根据它们的分布模式,死亡盒蛋白家族的一些成员被认为与胚胎发生、精子发生、细胞生长和分裂有关。作为这个家族的一员,这种基因产物的功能尚未确定另外,已经发现该基因的剪接转录变体。[由RefSeq提供,2010年6月]DEAD box proteins characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The function of this gene product which is a member of this family, has not been determined. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2010]
DHX35突变与药物:

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