DHX9靶向药基因

基因名称:DHX9  (DExH-box helicase 9)

别名: LKP,RHA,DDX9,NDH2,NDHII
基因ID:1660
Chromosome(GRCh37) :1 Start: 182808439 End: 182857117 Strand:
信号通路:
靶向药:
化疗药:

简介:这个基因编码一个含有DEAH的RNA解旋酶家族的成员编码蛋白是一种酶,催化双链RNA和DNA-RNA复合物的ATP依赖性解链这种蛋白质定位于细胞核和细胞质,并起转录调节作用。这种蛋白也可能参与逆转录病毒rna的表达和核输出。交替剪接导致多个转录变体。在11号和13号染色体上发现了该基因的假基因。[由RefSeq提供,2010年2月]This gene encodes a member of the DEAH-containing family of RNA helicases. The encoded protein is an enzyme that catalyzes the ATP-dependent unwinding of double-stranded RNA and DNA-RNA complexes. This protein localizes to both the nucleus and the cytoplasm and functions as a transcriptional regulator. This protein may also be involved in the expression and nuclear export of retroviral RNAs. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 11 and 13.[provided by RefSeq, Feb 2010]
DHX9突变与药物:

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