基因名称:DIS3L2 (DIS3 like 3′-5′ exoribonuclease 2)
别名: FAM6A,PRLMNS,hDIS3L2
基因ID:129563
Chromosome(GRCh37) :2 Start: 232826293 End: 233208678 Strand:
信号通路:
靶向药:
化疗药:
简介:该基因编码的蛋白质在序列上与rna外显体的3’/5’外核溶解亚基相似。外显子是一个大的多聚核苷酸复合物,负责降解各种rna底物。已经发现了一些转录变体,有些是蛋白质编码的,有些不是。[由RefSeq提供,2012年3月]The protein encoded by this gene is similar in sequence to 3’/5′ exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Mar 2012]
DIS3L2突变与药物: