基因名称:EIF1AX (eukaryotic translation initiation factor 1A, X-linked)
别名: EIF1A,EIF1AP1,EIF4C,eIF-1A,eIF-4C
基因ID:1964
Chromosome(GRCh37) :X Start: 20142636 End: 20159962 Strand: -1
信号通路:
靶向药:
化疗药:
简介:这个基因编码一个重要的真核细胞翻译起始因子。这种蛋白是43S复合体(一个40S亚单位,eif2/gtp/met-trnai和eif3)与帽状RNA 5’端结合所必需的。This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5′ end of capped RNA.
EIF1AX突变与药物:
MUTATION
药物:
Ziv-阿柏西普
疾病:
葡萄膜黑色素瘤