基因名称:ERF (ETS2 repressor factor)
别名: PE2,CRS4,PE-2,CHYTS
基因ID:2077
Chromosome(GRCh37) :19 Start: 42751717 End: 42759309 Strand:
信号通路:
靶向药:
化疗药:
简介:ets2是一种转录因子和原癌基因,参与端粒酶的发育、凋亡和调控。该基因编码的蛋白与ets2启动子结合,是ets2转录的一个强抑制因子。已经发现了编码两种不同亚型的转录变体。[由RefSeq提供,2015年8月]ETS2 is a transcription factor and protooncogene involved in development, apoptosis, and the regulation of telomerase. The protein encoded by this gene binds to the ETS2 promoter and is a strong repressor of ETS2 transcription. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
ERF突变与药物: