基因名称:ETS2 (ETS proto-oncogene 2, transcription factor)
别名: ETS2IT1
基因ID:2114
Chromosome(GRCh37) :21 Start: 40177231 End: 40196879 Strand: 1
信号通路:
靶向药:
化疗药:顺铂 紫杉醇
简介:该基因编码一种调节参与发育和凋亡的基因的转录因子。编码蛋白也是一种原癌基因,并被证明与端粒酶的调节有关。该基因的一个假基因位于X染色体上。选择性剪接导致多个转录变体。This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants.
ETS2突变与药物:
RS461155
药物:
顺铂 紫杉醇 疾病:
非小细胞肺癌