基因名称:EXOSC8 (exosome component 8)
别名: p9,CIP3,EAP2,OIP2,PCH1C,RRP43,Rrp43p,bA421P11.3
基因ID:11340
Chromosome(GRCh37) :13 Start: 37574678 End: 37583751 Strand:
信号通路:
靶向药:
化疗药:
简介:这个基因编码一个3′-5’外核糖核酸酶,它与含有富含au元素的mrna特异性相互作用。编码的蛋白质是外显子复合体的一部分,外显子复合体对许多rna物种的降解非常重要。在6号染色体上发现了这个基因的假基因。〔RefSeq,2009〕This gene encodes a 3′-5′ exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2009]
EXOSC8突变与药物: