基因名称：FCGR2A （Fc fragment of IgG receptor IIa）
别名： CD32,CD32A,CDw32,FCG2,FCGR2,FCGR2A1,FcGR,IGFR2
基因ID：2212
Chromosome(GRCh37) ：1 Start: 161475220 End: 161493803 Strand: 1
信号通路：
靶向药：
化疗药：
简介：该基因编码许多免疫应答细胞表面发现的免疫球蛋白Fc受体基因家族的一个成员。该基因编码的蛋白质是一种在巨噬细胞和中性粒细胞等吞噬细胞上发现的细胞表面受体，参与吞噬和清除免疫复合物的过程。选择性剪接导致多个转录变体。This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
FCGR2A突变与药物：
H167R
药物：
Ziv-阿柏西普
疾病：
“乳腺癌”
