基因名称:FCGR2C (Fc fragment of IgG receptor IIc (gene/pseudogene))
别名: CD32,FCG2,CD32C,CDW32,IGFR2,FCRIIC
基因ID:9103
Chromosome(GRCh37) :1 Start: 161551129 End: 161571010 Strand:
信号通路:
靶向药:
化疗药:
简介:该基因编码在许多免疫应答细胞表面发现的低亲和力免疫球蛋白γ-fc受体家族的三个成员之一。编码蛋白是一种跨膜糖蛋白,可能参与吞噬和清除免疫复合物该基因的等位基因多态性导致编码和非编码变异。[由RefSeq提供,2012年4月]This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants. [provided by RefSeq, Apr 2012]
FCGR2C突变与药物: