基因名称：FOXO4 （forkhead box O4）
别名： AFX,AFX1,MLLT7
基因ID：4303
Chromosome(GRCh37) ：X Start: 70315999 End: 70323384 Strand:
信号通路：
靶向药：
化疗药：
简介：该基因编码一个有翼螺旋/叉头转录因子家族的O类成员。这类编码的蛋白质受到生长和分化相关因子的调节，表明它们在这些过程中发挥作用。该基因在x染色体上的易位与11号染色体上编码dna结合蛋白的果蝇trithorax基因同源物与白血病有关。已发现该基因编码不同亚型的多个转录变体。[由RefSeq提供，2010年1月]This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
FOXO4突变与药物：
