GABRP靶向药基因

1,041

基因名称:GABRP  (gamma-aminobutyric acid type A receptor pi subunit)

别名:
基因ID:2568
Chromosome(GRCh37) :5 Start: 170210723 End: 170241051 Strand:
信号通路:
靶向药:
化疗药:

简介:γ-氨基丁酸(GABA)A受体是介导中枢神经系统最快抑制性突触传递的多亚单位氯通道该基因编码的亚单位在包括子宫和卵巢在内的一些非神经组织中表达。该亚单位可以与已知的GABA A受体亚单位结合,并且该亚单位的存在改变了重组受体对如孕烯醇酮等调节剂的敏感性另外,已经发现该基因编码不同亚型的剪接转录变体[由RefSeq提供,2014年5月]The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded by this gene is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
GABRP突变与药物:

常见问题
  • 如何在体龙基因完成所需的检测项目 流程简述 :在线咨询 - 采样送检 - 付款检测 - 检测分析 - 报告结果
查看详情

相关内容

官方客服团队

为您解决烦忧 - 24小时在线 专业服务