基因名称：GATA2 （GATA binding protein 2）
别名： DCML,IMD21,MONOMAC,NFE1B
基因ID：2624
Chromosome(GRCh37) ：3 Start: 128198270 End: 128212028 Strand: -1
信号通路： 能量代谢
靶向药： 硼替佐米
化疗药：法舒地尔
简介：该基因编码一个锌指转录因子GATA家族的成员，该家族以它们在靶基因启动子区域结合的一致核苷酸序列命名。编码蛋白在调节参与造血和内分泌细胞谱系发育和增殖的基因转录中起着重要作用。选择性剪接导致多个转录变体。This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.
GATA2突变与药物：
EXPRESSION
药物：
硼替佐米
法舒地尔 疾病：
肺腺癌
