基因名称：GSK3B （glycogen synthase kinase 3 beta）
别名：
基因ID：2932
Chromosome(GRCh37) ：3 Start: 119540800 End: 119813264 Strand:
信号通路： 细胞增殖
细胞周期
免疫相关
侵袭和转移
肿瘤干细胞
靶向药：
化疗药：
简介：该基因编码的蛋白是一个属于糖原合酶激酶亚家族的丝氨酸苏氨酸激酶。它是葡萄糖稳态的负调节因子，参与能量代谢、炎症、内质网应激、线粒体功能障碍和凋亡途径。这种基因的缺陷与帕金森病和阿尔茨海默病有关。[由RefSeq提供，2017年8月]The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017]
GSK3B突变与药物：
