HSP90AA1靶向药基因

基因名称:HSP90AA1  (heat shock protein 90 alpha family class A member 1)

别名: EL52,HSPN,LAP2,HSP86,HSPC1,HSPCA,Hsp89,Hsp90,LAP-2,HSP89A,HSP90A,HSP90N,Hsp103,HSPCAL1,HSPCAL4,HEL-S-65p
基因ID:3320
Chromosome(GRCh37) :14 Start: 102547075 End: 102606086 Strand:
信号通路: 细胞增殖
靶向药:
化疗药:

简介:该基因编码的蛋白质是一种可诱导的分子伴侣,具有同源二聚体的功能。编码的蛋白质通过协同伴侣调节的atp酶活性有助于特定靶蛋白的正确折叠。已经发现了两个编码不同亚型的转录变体。[由RefSeq提供,2012年1月]The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
HSP90AA1突变与药物:

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